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Symbol
Name
ID
Bcl2l11
BCL2 like 11
MGI:1197519
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
decreased B cell apoptosis
decreased thymocyte apoptosis
decreased T cell apoptosis
decreased splenocyte apoptosis
abnormal B cell proliferation
enlarged spleen
increased spleen weight
spleen hyperplasia
abnormal leukopoiesis
increased immature B cell number
increased transitional stage B cell number
increased double-negative T cell number
decreased double-positive T cell number
increased erythrocyte cell number
decreased mean corpuscular hemoglobin
increased granulocyte number
thrombocytopenia
increased mature B cell number
increased B-2 B cell number
increased follicular B cell number
increased marginal zone B cell number
increased B cell number
increased NK cell number
abnormal CD4-positive, alpha-beta T cell number
increased CD4-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
increased regulatory T cell number
increased T cell number
decreased lymphocyte cell number
increased lymphocyte cell number
increased large unstained cell number
increased monocyte cell number
increased leukocyte cell number
abnormal B cell morphology
abnormal plasma cell morphology
abnormal NK cell morphology
abnormal spleen morphology
abnormal spleen marginal zone morphology
abnormal splenic cell ratio
increased splenocyte number
abnormal lymphocyte physiology
abnormal B cell physiology
increased IgA level
increased IgG level
increased IgM level
increased immunoglobulin level
abnormal CD8-positive, alpha-beta T cell physiology
Availability Mouse Genotype
Bcl2l11em1(IMPC)H/Bcl2l11em1(IMPC)H
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast *
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui
Bcl2l11tm1Sjk/Bcl2l11tm1Sjk
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui
Bcl2l11tm3Rjd/Bcl2l11tm3Rjd
Bcl2l11tm4Boul/Bcl2l11tm4Boul *
Bcl2l11tm4Rjd/Bcl2l11tm4Rjd *
Bcl2l11tm5Boul/Bcl2l11tm5Boul *
Bcl2l11tm1.1Ast/Bcl2l11+
Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui
Bcl2l11tm6.1Boui/Bcl2l11tm6.1Boui
Foxp3tm4(YFP/icre)Ayr/Foxp3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory